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Brain Advance Access published online on May 21, 2008

Brain, doi:10.1093/brain/awn090
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© The Author (2008). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Reply: A plea for confidence intervals and consideration of generalizability in diagnostic studies

Chris Frost and Constantinos Kallis

Medical Statistics Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK

Correspondence to: Chris Frost, Medical Statistics Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK E-mail: Chris.Frost@lshtm.ac.uk

Received March 20, 2008. Accepted April 18, 2008.

The first 10% of the full text of this article appears below.

Sir, We read with interest the recent article by Klöppel and colleagues (2008Go) on automatic classification of MR scans in Alzheimer's disease and the coverage on the BBC's website. In particular, we were concerned . . . [Full Text of this Article]


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